Low testosterone (“T”) levels may be a terrible reality for millions of Americans. After all, it may exacerbate conditions like depression, hair loss, and erectile dysfunction (ED). This may significantly affect your daily life and confidence.
There is, thankfully, good news. Numerous drugs with a testosterone basis can help raise testosterone to healthy levels. These drugs are available as injections, patches, gels, and many other forms. Additionally, they can be useful for some people seeking hormone therapy that is gender-affirming.
An important sex hormone, particularly for men, is testosterone. Although it is produced by your body naturally, it can also be taken as medicine. Many people inject testosterone into a muscle or under their skin.
Modifications have been made to injectable testosterone so that it can remain in your body for days to weeks without degrading. Esters of testosterone are these altered forms of the hormone. Three distinct testosterone esters, testosterone cypionate, enanthate, and undecanoate, can help raise your testosterone levels.
These testosterone esters vary in various ways, but their duration in your body is the key distinction. The shortest-lasting form of testosterone in your body is enanthate. The longest-lasting form of testosterone is testosterone undecanoate, which lasts longer than testosterone cypionate.
Other differences affect logistics. For instance, while some injectables must be administered by a medical professional, others can be safely administered at home. They are all possibilities for you to think about.
A typical kind of injectable testosterone is testosterone cypionate (Depo-Testosterone). It is injected into your buttock muscle every one to four weeks and is available as both a brand-name and generic medication. It can be injected at home or given to you by a medical professional.
The range of testosterone cypionate dosages that are advised is 50 mg to 400 mg. Depending on your age, how you react to the drug, and any potential side effects, your doctor will choose and modify your dose.
This drug is used to treat men who do not produce enough of the hormone testosterone, which is necessary for the growth and development of the genitals, muscles, and bones, as well as the normal onset of puberty in boys. Testosterone is a member of the androgen drug class and affects a variety of body systems to allow the body to develop and function normally. Testosterone may also be synthesized naturally. Testosterone may also be synthesized naturally.
This medication is injected into the buttock muscle once every one to four weeks as directed by your doctor. Don’t inject this medication intravenously. The dosage depends on your medical background, testosterone levels in your blood, and how you respond to treatment.
Before using this medication on yourself at home, be sure to fully understand all preparation and usage instructions from your healthcare provider.
Use this medication frequently to get the most out of it. To help yourself remember, mark the days on a calendar when you will receive an injection.
Teenagers who misuse or abuse testosterone run the risk of developing major side effects like heart disease (including heart attack), stroke, liver disease, mental/mood issues, abnormal drug-seeking behavior, and inappropriate bone growth. use this medicine exactly as prescribed without ever increasing the dosage, frequency, or duration of use. You may have withdrawal symptoms (such as exhaustion, irritability, and sadness) after suddenly quitting testosterone use when the hormone is abused or misused. These signs could last for several weeks or even months.
An alternative form of injectable testosterone is the testosterone enanthate. There are two alternative ways to administer it.
An under-the-skin injection of testosterone enanthate is administered under the brand name Xyosted. Various other variations are injected intramuscularly (IM).
Under-the-skin injection: A weekly dose of 75 mg of Xyosted is advised. You can administer it intravenously at home.
IM injection: Numerous generic forms of testosterone enanthate are administered via buttock injection. Every one to four weeks, you can receive 50 mg to 400 mg.
Your specific testosterone enanthate dosage, like that of testosterone cypionate, will depend on how you respond to treatment, how old you are, and any adverse effects. But compared to testosterone cypionate, this form of testosterone may be slightly more quickly metabolized by your body.
Licensed applications for testosterone enanthate
Compared to other injectable testosterones, testosterone enanthate has more approved uses when administered as an IM injection. It can cure:
- Adolescents whose puberty is delayed
- Low testosterone in adult males (hypogonadism)
- Metastatic breast cancer in adults
However, only adult men with low testosterone are eligible to receive treatment with Xyosted, testosterone cypionate, and testosterone undecanoate .
A more recent brand-name injectable testosterone product is testosterone undecanoate (Aveed). It’s an IM injection that a medical professional gives you in the buttocks.
The fact that you can administer testosterone undecanoate injections less frequently than conventional injections is a benefit. You can skip 10 weeks (or 2.5 months) between doses if your body has gotten used to it.
A 750 mg dose of testosterone undecanoate is advised. Four weeks after the initial treatment, you will receive another shot. After your third treatment, you can begin getting your doses every 10 weeks.
The researchers, who presented their findings at the 9th European Congress on Obesity in Lyon, France, looked at overweight men who were given testosterone injections for up to five years to treat erectile dysfunction and other low testosterone symptoms, which can include, among others, a loss of sex drive, depression, brittle bones, and difficulty concentrating. A researcher named Farid Saad, DVM, claimed that the weight reduction “was an incidental finding that was entirely unexpected.”
During the first six weeks of treatment, two testosterone injections were given to each man in the study, followed by one injection every three months. The longest-treated males shed more than 30 pounds on average while also experiencing improvements in their blood pressure, LDL cholesterol, and blood sugar levels.
Obese males frequently have low testosterone levels. Increased estrogen levels are a result of being overweight, and this lowers testosterone levels. As a result, overweight men who lose weight can naturally raise their testosterone levels.
Low testosterone levels are a risk factor for prostate cancer and may be related to type 2 diabetes. Men who are thinking about testosterone therapy for any reason should explore natural testosterone boosters in addition to discussing the advantages and risks with their doctor.
The importance of testosterone in maintaining strong libido levels in both men and women has long been recognized. Given that they believe they can rely solely on estrogen for this, many girls would be shocked to learn this.
The truth is that everyone needs a sufficient amount of testosterone in their bloodstream at all times – for libido as well as many other essential body processes that can be recognized by reading some of the other articles on this website.
Which testosterone is best for libido is a common issue, particularly when changes in sexual desire and arousal become apparent.
Here are some examples where the gender differences are clear:
Typically, testosterone therapy is prescribed as a bioidentical cream formulation that is compounded in the pharmacy to the precise dosage requirements established by the hormone replacement physician for women, whose dosing requirements differ greatly from those of their male counterparts. Increased libido, sexual excitement, vaginal lubrication, and pleasure are all benefits of this treatment.
Other viable options are available to men, with injections being the most frequently suggested choice based on effectiveness and cost. While there are other options, such as patches, gels, and oral pellets that stick to the gums, testosterone injections continue to be the most popular option for men who want to increase libido and enhance their general health and physical well.
When it comes to your gains, testosterone can be a stomach hit. Despite giving it your all in the gym, you feel sore—and frequently weaker—after the pump.
That’s because testosterone is essential for maintaining muscle mass and strength. You’ll experience unpleasant symptoms like weight gain, weariness, and, yes, muscle loss if your levels plummet to a below-normal range.
Even though testosterone injections are not the same as using anabolic steroids, testosterone replacement therapy (TRT) can help you increase muscle growth by bringing your hormone levels back into balance. However, it is not a quick fix. In the first three months of treatment, you might notice changes in lean body mass and muscle strength, but it might take a year or longer to see the full effects.
How Does Low T Affect the Growth of Muscle?
By attaching to androgen receptors, which are proteins in your muscles, testosterone promotes muscle growth.
Even if you spend hours strength training, if your T levels are lower than they should be for your age, there simply isn’t enough of the hormone to activate the androgen receptors and promote increases
To gain muscle, testosterone injections stimulate the IGF-1 and androgen receptors in your muscle fibers. However, TRT shouldn’t be used unless you have a low testosterone level. You should order a test to examine your levels if you think low T is the cause of your inability to gain muscle.
Antares Pharma, Inc. (2022). Xyosted [package insert].
Bhasin S., et al. (2018). Testosterone therapy in men with hypogonadism: An endocrine society clinical practice guideline.The Journal of Clinical Endocrinology & Metabolism.
Bryant Ranch Prepack. (2022). Testosterone cypionate [package insert].
Endo Pharmaceuticals. (2021). Aveed [package insert].
Hikma Pharmaceuticals USA Inc. (2021). Testosterone enanthate [package insert].
Shoskes J.J., et al. (2016). Pharmacology of testosterone replacement therapy preparations.Translational Andrology and Urology.
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